In this poster you will see how T cells develop and differentiate within bone marrow, the thymus, and blood. You will also find all the T cell receptors present during these stages of the T cell life cycle and the transcription factors and cytokines involved at each step.
What is included?
Thymus seeding progenitors
CD presenting bone marrow–derived progenitors
Signals involved with TCR rearrangement including Notch, LEF, TCF1, and RUNX1
Including MHC-II selected, high, and intermediate MHC affinity
T helper and cytotoxic cells moving into the blood and to undergo further differentiation