T-cell development poster

In this poster you will see how T cells develop and differentiate within bone marrow, the thymus, and blood. You will also find all the T cell receptors present during these stages of the T cell life cycle and the transcription factors and cytokines involved at each step.

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What is included?

  • Thymus seeding progenitors

     CD presenting bone marrow–derived progenitors

  • TCR rearrangment

    Signals involved with TCR rearrangement including Notch, LEF, TCF1, and RUNX1

  • MHC selection

    Including MHC-II selected, high, and intermediate MHC affinity

  • Blood circulation

    T helper and cytotoxic cells moving into the blood and to undergo further differentiation