Necroptosis analysis guide

Necroptosis is a programmed form of necrosis that is dependent on activation of receptor-interacting kinase 3 (RIPK3)1 and the mixed lineage kinase domain-like (MLKL) pseudokinase2. This form of cell death is morphologically distinct from apoptosis, involving membrane rupture and release of cytoplasmic contents.

Learn more about this area with our comprehensive guide.

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Our guide includes

  • Molecular mechanisms

    Understand the molecular mechanisms of necroptosis, pyroptosis and ferroptosis

  • Distinct hallmarks

    Learn to recognize the distinct hallmarks that define non-apoptotic cell death

  • Tips and tricks

    Discover useful tips and tricks to differentiate between non-apoptotic cell death types

  • Recommended products

    Find out what tools are available for your necroptosis research