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2
PINK1
activation through autophosphorylation at S228
3
Ubiquitin
phosphorylation at S65
4
Parkin
recruitment
5
Parkin
is activated by
phosphorylation at S65 and by binding to phosphorylated ubiquitin, which was earlier phosphorylated at S65 by PINK1
6
Parkin
dependent
outer mitochondrial membrane (OMM) substrate ubiquitination
7
Recruitment of
autophagy receptors
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Products to help you explore the target of interest in the Mitophagy pathway
Parkin
| Antibody Anti-Parkin antibody [PRK8] | ab77924 |
|---|---|
| KO cell line Human PARK2 (Parkin) knockout SH-SY5Y cell lysate | ab280101 |
| Protein Recombinant Human Parkin protein | ab140806 |
| Biochemical Rutaecarpine, Indoloquinazoline alkaloid | ab141145 |
| ELISA Human Parkin ELISA Kit | ab212159 |
| Antibody Recombinant Alexa Fluor® 488 Anti-PARK7/DJ1 antibody [EP2815Y] | ab203989 |
| Antibody Recombinant Alexa Fluor® 647 Anti-PARK7/DJ1 antibody [EP2815Y] | ab204009 |
| Antibody Recombinant Alexa Fluor® 594 Anti-PARK7/DJ1 antibody [EP2815Y] | ab215102 |
TOM
| Antibody Recombinant Anti-TOMM20 antibody [EPR15581-54] - Mitochondrial Marker | ab186735 |
|---|---|
| Biochemical Pitstop® 2, Novel cell-permeable clathrin inhibitor | ab120687 |
| Antibody Recombinant Alexa Fluor® 488 Anti-TOMM20 antibody [EPR15581-39] - Mitochondrial Marker | ab205486 |
| Antibody Recombinant Alexa Fluor® 647 Anti-TOMM20 antibody [EPR15581-39] - Mitochondrial Marker | ab205487 |
| Antibody Recombinant HRP Anti-TOMM20 antibody [EPR15581-39] - Mitochondrial Marker | ab205796 |
| Antibody Recombinant Alexa Fluor® 647 Anti-TOMM20 antibody [EPR15581-54] - Mitochondrial Marker | ab209606 |
| Antibody Recombinant HRP Anti-TOMM20 antibody [EPR15581-54] - Mitochondrial Marker | ab209951 |
| Antibody Recombinant Alexa Fluor® 405 Anti-TOMM20 antibody [EPR15581-54] - Mitochondrial Marker | ab210047 |
| Antibody ecombinant Alexa Fluor® 594 Anti-TOMM20 antibody [EPR15581-54] - Mitochondrial Marker | ab210665 |
| Antibody Recombinant Alexa Fluor® 568 Anti-TOMM20 antibody [EPR15581-54] | ab210841 |
| Antibody Recombinant Alexa Fluor® 555 Anti-TOMM20 antibody [EPR15581-39] | ab214409 |
| Antibody Recombinant Alexa Fluor® 555 Anti-TOMM20 antibody [EPR15581-54] - Mitochondrial Marker | ab221292 |
| Antibody Recombinant APC Anti-TOMM20 antibody [EPR15581-54] - Mitochondrial Marker | ab225341 |
| Antibody Recombinant PE Anti-TOMM20 antibody [EPR15581-54] | ab225342 |
LC3
| Antibody Recombinant Anti-LC3B antibody [EPR18709] - Autophagosome Marker | ab192890 |
|---|---|
| KO cell line Human MAP1LC3B knockout HepG2 cell line | ab277828 |
| Protein Recombinant Human LC3B protein | ab103506 |
| ELISA Human LC3A ELISA Kit | ab239432 |
| Antibody Recombinant Alexa Fluor® 647 Anti-LC3B antibody [EPR18709] - Autophagosome Marker | ab225383 |
| Antibody Recombinant Alexa Fluor® 488 Anti-LC3B antibody [EPR18709] - Autophagosome Marker | ab225382 |
Ubiquitin
| Antibody Anti-Ubiquitin antibody [EPR8830] | ab134953 |
|---|---|
| Antibody Anti-Ubiquitin (linkage-specific K48) antibody [EP8589] | ab140601 |
| Antibody Anti-Ubiquitin (linkage-specific K63) antibody [EPR8590-448] | ab179434 |
| Protein Recombinant Human Ubiquitin protein (His tag) | ab218616 |
| Antibody Alexa Fluor® 647 Anti-Ubiquitin (linkage-specific K63) antibody [EPR8590-448] | ab192489 |
| Antibody Alexa Fluor® 647 Anti-Ubiquitin (linkage-specific K48) antibody [EP8589] | ab204476 |
| Antibody Alexa Fluor® 647 Anti-Ubiquitin antibody [EPR8830] | ab205468 |
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