This poster features every step of the MAPK-ERK pathway. You will find Ras activation leading to the MAPK phosphorylation cascade.
You will also find various downstream targets including c-Jun, Fos, and STAT3.
What is included?
Activation of Ras leading to phosphorylation of Raf-1, MEK1/2, and ERK1/2
Binding of key transcription factors including c-Jun and Fos
Downstream proliferation, differentiation, and growth
Resulting in apoptosis, cell cycle and inflammatory response