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Overview


What are post-translational modifications? Post-translational modifications, or PTMs, are in vivo chemical modifications of a protein after its translation, which can occur at any step in the life of a protein. PTMs have been mainly studied in nucleated cells, and they are conserved from yeast to humans which demonstrates how essential they are for cellular function ability.

Listen in for an introduction to post-translational modifications.



Topics

  • Detecting ubiquitylation
  • Troubleshooting ubiquitylation detection
  • Historic overview of the ubiquitin system discovery and ubiquitin biology
  • Ubiquitin and its importance in human diseases
  • Phosphorylation
  • Detecting S/T/Y phosphorylation; identifying phosphorylation sites and elucidating the function of the modification
  • Troubleshooting phosphorylation


  • Watch now




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    Meet our presenter

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    Meet our presenter

    Professor Kevin Hiom

    Professor Kevin Hiom is the Pat McPherson Chair of Cancer Biology at the Biomedical Research Institute and Dundee Cancer Centre, at the Ninewells Hospital and Medical School.

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