to see products
(A) Transcriptional dysregulation
KEY
Mutant huntingtin
Properly folded protein
Misfolded protein
Neurotransmitters
ub
Ubiquitin
(E) Mitochondrial dysfunction
Transport
Fusion
Biogenesis
PGC1a
(A)
(B)
(C)
(D)
(E)
(D)Disrupted neuronal circuitry
Dopamine
Glutamate
Trk-B
(B) Impaired protein degradation
ub
Autophagosome
formation
Autophagosome
transport
Cargo loading
Lysosomal fusion
Proteasome
(C)Altered protein folding
ub
Proteasome
Copyright© 2021 Abcam, All rights reserved
Products to help you explore the target of interest in the Huntington’s disease pathway
BDNF
| Antibody Recombinant Anti-BDNF antibody [EPR1292] | ab108319 |
|---|---|
| Protein Recombinant human BDNF protein | ab206642 |
| Biochemical LM22A-4, neurotrophic BDNF mimetic | ab222020 |
| ELISA Human BDNF ELISA Kit | ab212166 |
| Antibody Recombinant Alexa Fluor® 488 Anti-BDNF antibody [EPR1292] | ab222113 |
| Antibody Recombinant Alexa Fluor® 647 Anti-BDNF antibody [EPR1292] | ab222321 |
Trk-B
| Antibody Recombinant Anti-TrkB antibody [EPR17805-146] | ab187041 |
|---|---|
| KO cell line Human NTRK2 (TrkB) knockout HeLa cell line | ab261808 |
| Protein Recombinant human TrkB protein (Active) | ab174057 |
| Biochemical 7,8-Dihydroxyflavone (7,8-DHF), TrkB receptor agonist. Flavonoid. | ab120996 |
| ELISA Human TrkB ELISA Kit | ab264625 |
p62
| Antibody Antibody Recombinant Anti-SQSTM1 / p62 antibody [EPR4844] | ab109012 |
|---|---|
| KO cell line Human SQSTM1 (p62) knockout HEK293T cell line | ab255343 |
| Protein Protein Recombinant Human NMDAR2B protein | ab112298 |
| Biochemical Biochemical NMDA, excitotoxic amino acid | ab120052 |
| Antibody Recombinant Alexa Fluor® 488 Anti-SQSTM1 / p62 antibody [EPR4844] | ab185015 |
| Antibody Recombinant HRP Anti-SQSTM1 / p62 antibody [EPR4844] | ab194720 |
| Antibody Recombinant Alexa Fluor® 647 Anti-SQSTM1 / p62 antibody [EPR4844] | ab194721 |
| Antibody Antibody Recombinant Alexa Fluor® 594 Anti-SQSTM1 / p62 antibody [EPR4844] | ab203429 |
| Antibody Antibody Recombinant Alexa Fluor® 555 Anti-SQSTM1 / p62 antibody [EPR4844] | ab203430 |
| Antibody Recombinant APC Anti-SQSTM1 / p62 antibody [EPR4844] | ab225093 |
| Antibody Recombinant PE Anti-SQSTM1 / p62 antibody [EPR4844] | ab225094 |
| Antibody Recombinant Alexa Fluor® 647 Anti-SQSTM1 / p62 antibody [EPR18351] | ab225453 |
| Antibody Recombinant PE Anti-SQSTM1 / p62 antibody [EPR18351] | ab225454 |
HSP70
| Antibody Recombinant Anti-Hsp70 antibody [EPR16892] | ab181606 |
|---|---|
| Biochemical YM-08, blood-brain barrier permeable Hsp70 inhibitor | ab146424 |
| ELISA Human HSP70 ELISA Kit | ab187399 |
| Antibody Recombinant Alexa Fluor® 488 Anti-Hsp70 antibody [EP1007Y] | ab197870 |
| Antibody Recombinant PE Anti-Hsp70 antibody [EPR17677] | ab211769 |
| Antibody Recombinant Alexa Fluor® 555 Anti-Hsp70 antibody [EP1007Y] | ab223389 |
| Antibody Recombinant PerCP Anti-Hsp70 antibody [EP1007Y] | ab223390 |
| Antibody Recombinant PE Anti-Hsp70 antibody [EP1007Y] | ab223391 |
Don’t see the product you need in our catalog?
Interested in in-licensing opportunities?
“Alexa Fluor is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company”