ER stress is implicated in several disorders, including Alzheimer’s disease and Parkinson’s disease. The pathway can be induced by many factors and involves several genes.
In this poster you will find the pathways activated by stress response inflicted upon the endoplasmic reticulum. This includes apoptosis, proteasomal degradation of key proteins, mRNA splicing, and activation of unfolded protein response genes GRP78, PDI, and GRP94.
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