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Overview


In Alzheimer's disease, amyloid beta (Aß) plaques exhibit diverse conformations resulting in structural variants with distinct pathologies.

Listen in as Professor Charles Glabe, of the University of California, Irvine, reviews the structural variation of beta amyloid (Aβ) antibodies and discusses how Aβ can help further Alzheimer’s research.


This webinar will review

  • Conformational diversity of amyloids that accumulate in Alzheimer's disease
  • Why different types of amyloid accumulate at different times and places
  • Why single monoclonal antibodies do not recognize all conformations
  • Mechanism of antibody conformational specificity and immunoreactivity
  • Additional insight into antibody specificity


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    Meet our presenter

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    Meet our presenter

    Dr. Charles Glabe

    Dr. Charles Glabe received his Ph.D. from the University of California, Davis and Postdoctoral training at The Johns Hopkins University School of Medicine and UC San Francisco School of Medicine. His research program is focused on amyloid structural and conformational polymorphisms, and the role of different types of amyloid in disease pathogenesis.

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