Autophagy in ischemic stroke – interactive pathway

Stroke is an aspect of cardiovascular disease, resulting from an interruption of the blood supply to a part of the brain. Such an interruption can be caused by a clot blocking a blood vessel (ischemic stroke) or as a result of a blood vessel bursting (hemorrhagic stroke). Ischemic stroke accounts for around 80% of all strokes.

Recent studies have found autophagy to be a key regulatory factor in ischemic stroke, unveiling a new range of potential therapeutic targets for neuroprotection.

Explore the role of autophagy signaling pathways in ischemic stroke with our interactive pathway.

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Explore the role of autophagy in stroke:

  • Excitotoxicity

    Study the role of excitotoxicity in stroke

  • Hypoxia and HIF1

    Find out the link between HIF1, stroke, and autophagy

  • Energy deprivation

    Learn how energy deprivation contributes to phagophore formation

  • Other key factors

    Find the best tools to study the role of autophagy in stroke