Track key genes and molecular mechanisms involved in ALS:

Genetic mutations

Find out the role of mutations in DNA/RNA-regulating genes, such as C9orf72, SOD1, FUS, TARDBP, in ALS pathogenesis

Impaired proteasome function

Study the role of proteasome impairment in ALS

Autophagy dysregulation

Explore how autophagy dysregulation leads to the development of ALS

Glutamate-mediated excitotoxicity

Investigate the role of glutamate excitotoxicity in the ALS pathogenesis