Overview
Bivalent domains are thought to be controversial, yet crucial, regulatory hubs in the differentiation of stem cells.
Join Dr Philipp Voigt of the Wellcome Trust Centre for Cell Biology at the University of Edinburgh as he reviews the concepts of bivalent domains, the impact of nucleosomal asymmetry and bivalency, and current views on the functions and mechanisms of bivalent domains.
Topics
Concepts and key players of bivalent domains
Impact of nucleosomal asymmetry and bivalency
Current views on functions and mechanisms of bivalent domains
Open questions and future directions