Cell adhesion and metastasis poster


This poster provides an overview of this whole process from EMT up to angiogenesis. To find out more download your free copy of the poster right here. 

Metastasis is the process by which a primary tumor will spread throughout the host body to form a secondary tumor. This is a multi-step process which begins with tumor cell invasion through the extracellular matrix into the bloodstream. 

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Our poster covers

  • EMT

    Tumor cells will adapt  mesenchymal cell properties to migrate during metastasis. 

  • Invasion

    Gelatinase enzymes released by tumor cells, degrade collagen found in the basement membrane.

  • Intravasation

    Inflammation response induces vascular permeability by affecting endothelial cell-cell adhesions.

  • Secondary tumor

    Growth factors such as VEGF promote the formation of new blood vessels (angiogenesis).